![]() Molecular analysis of the luminal- and mucosal-associated intestinal microbiota in diarrhea-predominant irritable bowel syndrome. Carroll IM, Ringel-Kulka T, Keku TO, et al. Impact of preservation method and 16S rRNA hypervariable region on gut microbiota profiling. Smoking cessation alters intestinal microbiota: insights from quantitative investigations on human fecal samples using FISH. Biedermann L, Brülisauer K, Zeitz J, et al. Development of the human infant intestinal microbiota. Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO. Effect of germfree state on the capacities of isolated rat colonocytes to metabolize n-butyrate, glucose, and glutamine. ![]() Cherbuy C, Darcy-Vrillon B, Morel MT, Pégorier JP, Duée PH. Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118. Corr SC, Li Y, Riedel CU, O’Toole PW, Hill C, Gahan CGM. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL. Microflora modulates endocrine cells in the gastrointestinal mucosa of the rat. Uribe A, Alam M, Johansson O, Midtvedt T, Theodorsson E. To report SUSPECTED ADVERSE REACTIONS, contact Salix Pharmaceuticals at 1-80 or FDA at 1-80 or Please click here for full Prescribing Information. Advise pregnant women of the potential risk to a fetus. Dose adjustment of warfarin may be required. INR changes have been reported in patients receiving rifaximin and warfarin concomitantly.In clinical studies, the most common adverse reactions for XIFAXAN were:.In patients with hepatic impairment, a potential additive effect of reduced metabolism and concomitant P-gp inhibitors may further increase the systemic exposure to rifaximin. Concomitant administration of cyclosporine, an inhibitor of P-gp and OATPs, significantly increased the systemic exposure of rifaximin. Caution should be exercised when concomitant use of XIFAXAN and P-glycoprotein (P-gp) and/or OATPs inhibitors is needed.Caution should be exercised when administering XIFAXAN to these patients. There is an increased systemic exposure in patients with severe (Child-Pugh Class C) hepatic impairment.If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. Clostridium difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including XIFAXAN, and may range in severity from mild diarrhea to fatal colitis.Hypersensitivity reactions have included exfoliative dermatitis, angioneurotic edema, and anaphylaxis. XIFAXAN is contraindicated in patients with a hypersensitivity to rifaximin, rifamycin antimicrobial agents, or any of the components in XIFAXAN.Visit or call 1-866-XIFAXAN for full eligibility criteria, terms and conditions. ![]() Maximum benefits and other restrictions apply. Offer excludes full cash-paying patients. ![]() Patient must be enrolled in, and must seek reimbursement from or submit a claim for reimbursement to, a commercial insurance plan. †Patient is not eligible if he/she participates in or seeks reimbursement or submits a claim for reimbursement to any federal or state healthcare program with prescription drug coverage, such as Medicaid, Medicare, Medigap, VA, DOD, TRICARE, or any similar federal or state health care program (each a Government Program), or where prohibited by law. Salix Pharmaceuticals does not guarantee coverage or reimbursement for the product. It is the treating physician’s responsibility to determine the proper diagnosis, treatment and applicable ICD-10 Code. *The ICD-10 Codes and all other patient-access-related information are provided for informational purposes only. ![]()
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